Indian Journal of Research in Homoeopathy
Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study
Euphorbia tirucalli; Aveloz; Toxicology; High Dilutions; Mice
The latex extracted from Euphorbia tirucalli, a plant popularly known as Aveloz, is used in complementary medicine to induce tumor regression. However, as this latex has toxic effects when administered orally in ponderal doses, the present study was designed to assess the effects of high dilutions in healthy mice over a period of 18 weeks. The Aveloz latex-high diluted solutions (latex-HD) were obtained through the interaction of two processes: 1:100 dilution in mass and succussion, using ethanol 70% as a solvent, in the homeopathic dilutions of 5, 15 and 30cH, following Farmacopéia Homeopática Brasileira. Control solutions without latex were compounded (ethanolic-HD) in the same dilutions and were administered simultaneously. The animals which received latex-HD 30cH showed a significant increase in food consumption (p < 0.05) without significant difference in weight gain. In regards to water consumption, no statistical difference was shown when different Aveloz latex-HD groups were compared, apart from the group that received 1 drop of pure latex in water, which presented a significant increase (p < 0.05) in this parameter.
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Varricchio M, Pereira C, Sales F, et al. Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study. Indian J Res Homoeopathy [Internet]. 2009 Jan 01; 3(1):Article 2 1-5. Available from: https://www.ijrh.org/journal/vol3/iss1/2. Free full text article.