Intraepidermal squamous cell carcinoma in situ (Bowen's disease) managed with classical Homoeopathy: A case report

Authors

• Anastasia Leivada, Savvas Hospital, Athens, GreeceFollow
• Aaditi Lakshmana, Centre For Classical Homeopathy, Bengaluru, Karnataka, IndiaFollow
• Ioannis Constantaras, Vima Ygeias Clinic, Thessaloniki, GreeceFollow
• Seema Mahesh, Centre For Classical Homeopathy, Bengaluru, Karnataka, IndiaFollow
• George Vithoulkas, International Academy of Classical Homeopathy, Alonissos, GreeceFollow

Author ORCID Identifier(s)

Seema Mahesh: https://orcid.org/0000-0002-4765-5595

George Vithoulkas: https://orcid.org/0000-0002-9118-8306

Corresponding Author

Seema Mahesh

Keywords

Bowen's disease, Homoeopathy, Intraepidermal squamous cell carcinoma in situ, SCCIS

Article Type

Case Report

Abstract

Introduction: Bowen's disease, also known as intraepidermal squamous cell carcinoma in situ (SCCIS), is a pre-cancerous skin condition with the potential for progression into invasive carcinoma. Long-term exposure to ultraviolet (UV) radiation from sunlight is considered a primary causative factor, leading to DNA damage and subsequent cellular mutations within the epidermis. Conventional treatments are generally effective but may be associated with complications, including pain, local infection, scarring, pigmentation changes, and occasional recurrence. Case summary: This case report describes a 58-year-old male with Bowen's disease who experienced limited benefit from conventional treatments and sought homoeopathic therapy. The patient was treated with the homeopathic remedy ``Graphites'', selected on the basis of totality of symptoms, which eventually resolved the skin lesions and improved his overall physical and emotional well-being. This case highlights the potential of Homoeopathy as a complementary approach to managing Bowen's disease and preventing cancer progression, suggesting the need for further research to understand the benefits and mechanisms of homoeopathic treatment in such conditions.

Digital Object Identifier

10.53945/2320-7094.2395

Publisher

Central Council for Research in Homoeopathy

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.

How to cite this article

Leivada A, Lakshmana A, Constantaras I, et al. Intraepidermal squamous cell carcinoma in situ (Bowen's disease) managed with classical Homoeopathy: A case report. Indian J Res Homoeopathy. 2026;20(2):270–8.