Indian Journal of Research in Homoeopathy


homoeopathy; pharmacodynamic effects; homoeopathic pathogenetic trial; drug proving; paraffin

Article Type

Original Article


Objective: Objective of the study was to elicit the pharmacodynamic response of the drug Paraffin on healthy human volunteers in non-toxic doses. Methodology: Drug was proved through a double-blind method and multi-centric study. Trial drug was proved in three potencies (6C, 30C and 200C) on 43 volunteers who were declared apparently healthy during their pre-trial medical examination by medical specialists. The volunteers consumed 56 doses (four doses per day for fourteen days) of each potency (6C, 30C and 200C) in three stages for a varying period. The symptoms generated during the trial period were noted by the volunteers and elaborated and cross examined by the Proving Masters. The data obtained from different centers were compiled at proving-cum-data processing cell at CCRH headquarters after de-coding. Observation: Out of the 30 provers who were on actual drug trial, 13 manifested symptoms. Drug was able to produce symptoms in each potency more or less on every part of the body. Only a few symptoms appeared in more than one prover. Some of the symptoms have been reproved which are mentioned in the fragmentary provings published in different literature. Conclusion: Pharmacodynamic response is elicited from every part of the body. Symptoms appeared (new and reproved) during the proving trial will add to the literature available on the drug and benefit the research scholars and clinicians. The symptoms need to be verified through clinical application in different clinical conditions.

Digital Object Identifier



Central Council for Research in Homoeopathy



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.