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   2008| July-September  | Volume 2 | Issue 3  
    Online since April 11, 2014

 
 
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CLINICAL RESEARCH
Role of Cephalandra indica Q in the management of Diabetes Mellitus as an add-on medicine along with conventional antidiabetics
Hafeezullah Baig, SR Sharma, Anita Sharma, Praveen Oberai, Debadatta Nayak, Alok Mishra
July-September 2008, 2(3):22-27
Objective : To ascertain the role of Cephalandra indica Q, in the management of patients suffering from Diabetes mellitus (type I or type II) continuing on anti-diabetic treatment for maintenance of blood sugar levels and to identify its reliable indications. Material and Methods : An open, prospective, observational study was carried out during the period July 1992 - March 2000; 96 patients with post-prandial blood sugar level more than 160 mg/dL even after taking anti-diabetic medicine were enrolled for the study. All the patients were administered with Ceplalandra indica Q in the dosage, one drop per kilogram of their body weight. The dose was divided in three parts, mixed with one ounce of water and was given three times a day, until disappearance of all signs and symptoms along with control of Blood sugar level. Fasting and post-prandial blood and urine sugar levels were measured on every follow-up visit of the patient. Other required investigations were also conducted. All the patients were advised to take low calorie and high fibre diet, do regular physical exercise and to avoid physical and mental stress. Results : Out of 96 patients registered, 88 patients were followed up. Mean FBS level of patients before treatment was 138.90 ± 24.388 (range 83 to 216 mg/dL) where as mean FBS after treatment was 115.86 ± 26.363 (range 64 to 202 mg/dL). Mean PPBS level before treatment was 265.08 ± 44.675 (range 178 to 386 mg/dL) where as mean PPBS after treatment was 204.75 ± 39.968 (range 116 to 341 mg/dL). Dosage of allopathic medicines was reduced in maximum number of patients but, it was completely withdrawn in 17 patients. There was improvement in signs and symptoms, along with decrease in recurrence: no recurrence in 9 patients, recurrence with less intensity in 55. The indications for Cephalandra also verified. Conclusion : This study shows some positive role of Cephalandra indica Q in maintaining blood sugar level. Future controlled studies with Cephalandra indica alone vis-à-vis other conventional anti-diabetic medicines, by doing the required laboratory tests, are suggested to explore more about the hypoglycemic effect of Cephalandra indica.
  17,664 559 -
CLINICAL VERIFICATION
Ferrum Picricum: A Multicentric Clinical Verification Study conducted by CCRH*
PS Chakraborty, JP Singh, MK Rai, Pramodji Singh, AK Vichitra, A.K.N. Singh, Deepa Chakraborty, DK Singh, Hari Singh, Mohan Singh, MN Sinha, Rajpal Singh, RK Rai, S Prakash, SD Pathak, SR Bhagat, Vijay K Paul, VK Singh, Yogendar Rai, VA Siddiqui
July-September 2008, 2(3):15-21
Ferrum picricum is mentioned in the homoeopathic literature for diseases/complaints like anaemia, malaria fever, impaired hearing, vertigo, epistaxis, tinnitus, loss of voice, indigestion, headache, tired feeling, sexual excesses, loss of blood, constipation, prostate enlargement, warts and corns2. These indications needs clarification. An open multicentric clinical study at various Institutes / Units under Central Council for Research in Homoeopathy was conducted to confirm the use of Ferrum picricum as mentioned in homoeopathic materia medica and to add to its drug picture. For this 3,465 patients were enrolled in the study. The study not only confirms the therapeutic use of the drug in headache, vertigo, epistaxis, tinnitus aurium, loss of voice, constipation, enlargement of prostate, cough, corns, warts and debility, as mentioned in the homoeopathic literature, but also delineates the characteristics which could help in differentiating Ferrum picricum from other similar remedies. Beside, a set of new symptoms also emerged as clinical symptoms increasing the scope of use of this medicine in clinical practice and suggest a comprehensive proving to get full picture of the drug.
  4,688 402 -
EXTRA MURAL RESEARCH
Diabetes mellitus – Defining scope and clinical approach for homoeopathic management
NL Tiwari, Prashant Tamboli
July-September 2008, 2(3):28-36
The study was undertaken to explore if there was a definite role of homoeopathic medicines in the management of Diabetes Type 2 and, if so, to determine the role of Constitutional and Organ remedies in its management. The comprehensive role of the individual susceptibility and miasm in the management of diabetes was also been studied. 90 patients were studied by Randomized Single Blind Clinical Trial by dividing them into three groups - Constitutional, Organ and Placebo. In the later part of the study the Cross over design was adopted between the Constitutional group and the Placebo group. Results showed that at the end of the first 6 months of the trial, 67% patients improved from the constitutional group while the comparable figures from the Organ group and the Placebo group was 37% and 7% respectively. At the end of the trial 70% from the constitutional group improved as compared to 10% from the Organ remedy group and 7% from the placebo group. The study confirmed the efficacy of homoeopathic treatment in Diabetes type 2 and also established the indications for adopting the Constitutional and the Organ remedy approach to its management. In the process, the need to incorporate the study of individual susceptibility and miasmatic expressions in determining successful homoeopathic management and the parameters of assessing the susceptibility has been clearly defined.
  2,405 597 -
CASE RECORD
Menopausal Flushes: A bane for Women
Bindu Sharma
July-September 2008, 2(3):37-44
This case report highlights the positive role of homoeopathic treatment in the management of the endocrinal syndrome of 'Menopause'. The improvement registered was not only subjective but also on patho-physiological parameters. This is evident from the data with regard to subjective and objective manifestations and pathological investigations recorded at the commencement of treatment and on conclusion of the treatment. The improvement in psychosomatic manifestations was corroborated by improvement in hormonal levels where FSH level came down from 54.61 to 15.72 mIU/ml. The psychosomatic manifestations included anxiety and depression, palpitation, insomnia, memory lapses, mood swings, hot flushes and night sweats; all were alleviated with a drug not frequently used for climacteric ailments, i.e. Crotalus horridus. The common presenting symptoms of the patient were repertorized to arrive at this medicine, which is not so frequently used for menopausal complaints (an approach different from the conventional one of repertorizing individual characteristics of the patient).With this medicine other concomitant pathological conditions like Trichomonas vaginalis discharge, chronic cervicitis, Nabothian follicle and tenderness in the right fornix disappeared completely. The consultant Gynaecologist monitored the case throughout the study and she duly authenticated the finasl dings.
  1,552 373 -
DRUG PROVING
Ficus Religiosa: A multicentric double blind Homoeopathic Pathogenetic Trial (drug proving) carried out by CCRH*
NR Dey, KC Das, Yogendra Rai, VA Siddiqui, Rajpal Singh
July-September 2008, 2(3):10-14
Objective: Objective of the study was to elicit the pharmacodynamic response of the drug, Ficus religiosa on healthy human beings in non-toxic doses. Methodology: Drug was proved through a double-blind method and was a multi-centric study. Trial drug was proved in two potencies (30C and 200C) on 24 volunteers who were selected and declared apparently healthy during their pre-trial medical examination by specialists. The volunteers took 56 doses of each of the two potencies in three stages including one control stage for a varying period. The symptoms generated during the trial period were noted by the volunteers and elaborated and cross examined by the Proving Masters. The data obtained from different centers were compiled at proving-cum-data processing cell at CCRH headquarters after decoding the drug. Observation: Out of the 17 volunteers who were on actual drug trial, 11 manifested symptoms. Drug was able to produce symptoms in each potency more or less on every part of the body. Some of the symptoms have been reproved which are mentioned in the fragmentary provings published in different literatures. Conclusion: Symptoms appeared (new and reproved) during the proving trial will add to the literature available on the drug and benefit the research scholars and clinicians. This also needs verification through clinical application in different clinical conditions.
  1,537 331 -
FUNDAMENTAL RESEARCH
Theory and Instrumentation Related to Potentised Homoeopathic Medicines∗†
T Maity, D Ghosh, CR Mahata
July-September 2008, 2(3):1-5
This paper offers a theory for establishing the scientific basis of homoeopathic medicines followed by an instrumentation technique named as 'dielectric dispersion of ordered molecular groups of sugar of milk caused by potentised homoeo - medicines for verification of the proposed theory. Usually one studies anomalous dielectric dispersion of a material caused by intra-molecular binding forces of separate molecules. The authors of this paper extend this concept to ordered molecular groups. The theoretical analysis suggests that there will be anomalous dielectric dispersion at selected frequencies specific to shape, size and number of atoms in the ordered molecular group of the material. Now, homoeopathic medicines, as is felt by several modern investigators including the authors of this paper, are ordered molecular groups of the vehicle of potentisation. The instrumentation method, supported by the properly developed theory mentioned above, is described in this paper to observe the frequency domain signature of the sugar of milk soaked with homoeopathic medicine. The anomalous dielectric dispersion of the medicine-soaked sugar of milk, which occurred at acoustic resonant frequencies of the material, were observed repeatedly and recorded through the experimental arrangement. The results were further confirmed by blind experiments. Thus the experiments validate the theoretical model. Further, the experimental results and the nature of results obtained from MATLAB - simulation support each other giving additional confidence in the approach.
  1,543 269 -
DRUG STANDARDISATION
Pharmacognosy of Prunus laurocerasus Linn-A Homoeopathic Drug
P Padma Rao, K Janardhan Reddy, HC Gupta
July-September 2008, 2(3):6-9
Prunus laurocerasus L., a shrub belonging to family Rosaceae, is a well known drug in homoeopathy. Leaves are used as an antispasmodic, in heart diseases, for relief in nausea and as an ingredient in eye lotions. The leaves are coriaceous, dark green above and pale beneath, shortly petiolate; epidermal cells have distinctly thick, curved to wavy and sinuate sides; hypostomatic with anomocytic and anisocytic types of stomata. The mesophyll and midvein ground tissue possess characteristic sphaeraphidal idioblasts. Typical aerenchyma is present in ground tissue of leaf midvein and petiole. A layer of endodermis encloses the median arcuate vascular bundle of midvein and petiole.
  1,476 287 -
EDITORIAL
Editorial
C Nayak
July-September 2008, 2(3):0-0
  1,176 153 -
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