Efficacy of Ferrum metallicum 30C in restoring menstrual cycle in polycystic ovarian syndrome patients – A randomised, placebo-controlled, single-blind trial

Authors

J.P. Jerin, Chettinad Homoeopathy Medical School and Hospital, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India.Follow
Chaturbhuja Nayak, Homoeopathy University, Jaipur, Rajasthan, India.Follow
D. Karthikeyan, Central Council for Research in Homoeopathy-Clinical Research Unit for Homoeopathy, Puducherry, IndiaFollow
Maanasa Rajagopal, Independent Researcher, Chennai, Tamil Nadu, India.Follow

Author ORCID Identifier(s)

https://orcid.org/my-orcid?orcid=0000-0001-9646-0607

Corresponding Author

J.P. Jerin

Keywords

Ferrum metallicum, Homoeopathy, Menstrual irregularities, Polycystic ovarian syndrome (PCOS), Polycystic ovarian syndrome questionnaire, RCT.

Article Type

Original Article

Abstract

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age, with the prevalent clinical symptom of irregular menstruation.

Objective: This trial assessed the efficacy of Ferr. met. 30C in restoring the menstrual cycle among PCOS patients.

Methods: A randomised, placebo-controlled, single-blind trial was conducted at outpatient departments of Sri Sai Ram Homoeopathy Medical College and Research Centre, Chennai. Patients were randomly allotted to the experimental (Group I - Ferr. met. 30C) and control (Group II - Placebo) groups. Quality of life of patients in both groups was assessed through PCOS Questionnaire scale at baseline and at 6th month.

Results: Sixty-five patients were enrolled and randomly assigned to Group I (n = 33) and Group II (n = 32). The menstrual cycle got regularised in 48% of Group I patients and 29% of Group II. Data were also compared to see the menstrual restoration period in both the groups. About 48% of participants in group I and 29% in group II had their menses restored after homoeopathic intervention and the difference between the groups was found to be 1.81 (p < 0.05). Improvement in menstrual cycle before and after intervention for patients in both groups showed a significant difference after the intervention (higher in Group I than Group II), confirming the efficacy of intervention in the experimental group: p < 0.05.

Conclusion: This trial suggests that Ferr. met. 30C could be effective in restoring the menstrual cycle in PCOS patients. Rigorous trials and independent replications are warranted.

Digital Object Identifier

10.53945/2320-7094.1979

Publisher

Central Council for Research in Homoeopathy

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.

How to cite this article

Jerin JP, Nayak C, Karthikeyan D, Rajagopalan M. Efficacy of Ferrum metallicum 30C in restoring menstrual cycle in polycystic ovarian syndrome patients – A randomised, placebo-controlled, single-blind trial. Indian J Res Homoeopathy 2024;18:236-244.