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A multicentric observational study to evaluate the role of homoeopathic therapy in vitiligo
PS Chakraborty1, Subhash Kaushik2, Lipipushpa Debata3, Bhola Ram4, Ravi Kumar5, Mahesh Shah6, DK Jha3, Dubashi Ramesh7, Maya Padmanabhan8, C Nayak8, Vikram Singh8
1 Scientist-4, Dr. Anjali Chatterjee Regional Research Institute (H), Kolkata, India
2 Scientist-4, Central Research Institute (H), NOIDA, India
3 Scientist-1,Scientist-3, Regional Research Institute (H), Puri, India
4 Scientist-3, Regional Research Institute (H), Gudivada, India
5 Scientist-4, Clinical Research Institute (H), Chennai, India
6 Scientist-4, Homoeopathic Drug Research Institute, Lucknow, India
7 Scientist-3, Drug Standardisation Unit (H), Hyderabad, India
8 Statistician, Former Director General, Deputy Director (H), CCRH, Headquarters, New Delhi, India
Correspondence Address:
Lipipushpa Debata
Regional Research Institute (H), Marchikote Lane, Puri, Odisha - 752 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-7168.166378
Clinical trial registration CTRI/2012/04/002591.
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Background: Vitiligo has an immense psychological impact on the affected individual and a reason for low self-esteem. Considering the disappointing outcomes, A multicentric open clinical study was undertaken by the Central Council for Research in Homoeopathy, at five institutes and units in India from October 2005 to September 2010.
Aims and Objectives: This observational study aimed to see the usefulness of homoeopathic therapy in the management of vitiligo.
Materials and Methods: 432 patients of all age groups suffering from vitiligo were enrolled in the study. Out of that, 169 patients completed 2 years of follow-up and were considered for analysis. Homoeopathic medicines, based on the totality of symptoms and repertorization were prescribed. The analysis of the cases was based on the Vitiligo Symptom Score (VSS) and photographs of the patients. Result was analyzed using statistical method of SPSS version 20.
Results: The changes in the mean VSS at intervals of every 6 months was found to be statistically significant. Homoeopathic treatment was found to be useful in relieving vitiligo in varying degrees in 126 patients, out of which 4 (2.94%) cases showed marked improvement, 15 (11.03%) cases showed moderate improvement, 77 (56.62%) cases showed mild improvement, and 30 patients although improved, fell in the category of not significant improvement group (below 25% improvement). Ten homoeopathic medicines were found useful in the study of which Sulphur (n = 27), Arsenicum album (n = 19), Phosphorus (n = 19), and Lycopodium clavatum (n = 10) were the most commonly indicated and useful medicines. |
