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   2008| January-March  | Volume 2 | Issue 1  
    Online since April 15, 2014

 
 
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EXTRA MURAL RESEARCH
Study on effectiveness of homoeopathic bowel nosodes in the treatment of cervical spondylosis on the basis of stool culture report
Chaturbhuja Nayak
January-March 2008, 2(1):42-48
A prospective study of the patients suffering from cervical spondylosis treated with bowel nosodes was conducted with the objective to study their efficacy when prescribed on the basis of stool culture report. The stool cultures of 82 enrolled cases were done for isolation of non-lactose fermenting bowel organisms. On the basis of the presence of the predominant bacteria in the stool of patient suffering from cervical spondylosis, the corresponding bowel nosode was administered. Out of 82 patients enrolled in this study, 31 patients were given bowel nosodes only; 69 patients (84.14%) were given bowel nosode alone or along with homoeopathic/biochemic medicines. The results of the study were, therefore, assessed in these 69 patients only. The study concluded that bowel nosodes could possibly be used effectively on the basis of the stool culture in the treatment of patients suffering from cervical spondylosis.
  2,214 392 -
CLINICAL RESEARCH
Clinical evaluation of homoeopathic medicines in sinusitis
SR Sharma, K Bhanu Murty, GC Sahagal, Bindu Sharma, K.S.V. Bharatalaxmi, K Raju, S Ravi Kumar
January-March 2008, 2(1):26-37
Objectives: This study aimed to evolve a group of most effective homoeopathic medicines in the management of sinusitis, to identify their reliable indications, most useful potencies, frequency of administration, and their relationship with other medicines. Methods: An open, multi-centric, prospective, observational study was carried out during the period 1985 -2003. A total of 950 patients (424 males, 526 females), of both acute and chronic type, were registered on the basis of subjective and/or objective symptoms of sinusitis. Patients presenting with the complications of sinusitis or requiring hospitalization were excluded from the study. Homoeopathic medicines in different potencies (Q, 6, 30, 200 & 1M) were administered according to their prescribing indications. All the enrolled patients were treated for the period ranging from 1 month to 6 years depending upon acute or chronic nature of the disease condition. Besides homoeopathic intervention, patients were advised to follow general measures like steam inhalation and to avoid cold exposure. Results: Different clinical patterns were observed, viz. acute/chronic, frontal, fronto-maxillary (mixed), sphenoidal, ethmoidal and maxillary sinusitis. Three hundred and ninety four patients were followed up, out of which 138 patients were cured with no relapse after a follow up period of one year; varying degrees of improvement were seen, viz. marked improvement in 80 patients, moderate improvement in 91 patients, mild improvement in 66 patients. While 04 patients showed aggravation of their condition, 15 patients did not improve. In 141 patients of fronto-maxillary sinusitis, objective symptoms were relieved. Belladonna (n=16), Kali bichromicum (n=21), Nux vomica (n=14), Rhus toxicodendron (n=15), and Silicea (n=21) were found to be useful medicines in comparision to other medicines. Conclusion: This long term observational study indicated a positive role of homoeopathic medicines in the management of sinusitis. A group of medicines have been identified which have benefited the patients, when used on the basis of prescribing indications.
  1,341 393 -
CASE RECORD
A case of vitiligo treated with phosphorus
S Ravi Kumar
January-March 2008, 2(1):49-57
Vitiligo a disease of cosmetic problem has much psychosocial impact. The success rate in treating this condition in conventional medicines is limited and sometimes, treatment follows with side effects. Though a few case records are documented in the past about the success of various homoeopathic medicines, yet they lack proper quantitative assessment. This is a case documented from the ongoing clinical research study on vitiligo at Clinical Research Unit (Homoeopathy), Chennai. The case was treated with Phosphorus over a period of 17 months with steady improvement which is evident from the photographs and improvement in baseline scores of presentation of the case. The outcome of the ongoing multicentric clinical research study will reveal further regarding the effect of homoeopathic medicine in Vitiligo.
  1,256 383 -
DRUG PROVING
Argemone mexicana: A multicentric double blind Homoeopathic Pathogenetic Trial (Drug Proving) carried out by CCRH
NR Dey, KC Das, Yogender Rai
January-March 2008, 2(1):13-18
Objective : Objective of the study was to elicit the pharmacodynamic response of the drug, Argemone mexicana (prickly poppy) on healthy human volunteers, in non-toxic doses. Methodology : The drug was proved through a double-blind placebo controlled technique and is a multi-centric study. Trial drug was proved in three potencies (200C, 30C and 6C) on 38 volunteers who were selected and declared apparently healthy during their pre-trial examination by specialists. The volunteers took the three potencies (56 dozes of each potency ) in three stages for a varying period. The symptoms generated during the trial period were noted by the provers and elaborated and cross examined by the Proving Masters. The data obtained from different centers were compiled at proving-cum-data processing cell at CCRH headquarters after de-coding. Observations : Out of the 25 provers who were on actual drug trial, 18 manifested symptoms. Drug was able to produce symptoms in each potency more or less on every part of the body. Only a few symptoms appeared in more than one prover. Some of the symptoms mentioned in different literatures after fragmentary provings have been reproved. Conclusion : Symptoms appeared (new and reproved) during the proving trial will add to the literature available on the drug and benefit the research scholars and clinicians. This also needs verification through clinical application in different settings.
  1,242 286 -
CLINICAL VERIFICATION
Amoora rohituka: A multicentric clinical verification study conducted by CCRH
PS Chakraborty, JP Singh, MK Rai, Pramodji Singh, Hari Singh, ER Bhagat, VA Siddiqui, AK Vichitra, A.K.N. Singh, DK Singh, Mohan Singh, MN Sinha, Rajpal Singh, RK Rai, S Prakash, SD Pathak, Vijay K Paul, VK Singh, Yogendar Rai, Deepa Chakraborty
January-March 2008, 2(1):19-25
Amoora rohituka or Andersonia has been used by Indian physicians as a medicine for splenic disorders since longtime. In Ayurvedic literatures it has been mentioned as an alterative, astringent and a tonic for liver and spleen enlargement. In Homoeopathy, it has been used for conditions like constipation, prolonged fevers associated with enlargement of spleen and liver; headache and burning pain in eyes, face, hands, feet, stomach, nausea & vomiting etc. A total of 4706 patients participated in this multicenteric clinical study at various Units/Institutes under Central Council for Research in Homoeopathy to confirm the uses of Amoora rohituka as mentioned in the homoeopathic materia medica and to evolve its clinical drug picture. This study not only confirms its therapeutic use in constipation , headache, fever, enlargement of liver and spleen and burning pain in different parts of the body etc. as noted in literature, but has also delineated the characteristics, which would help in differentiating Amoora rohituka from other similar remedies given in homoeopathic materia medica. Besides, a set of other symptoms were also relieved by the same drug, given for other purpose and emerged as clinical symptoms.
  1,211 278 -
EXTRA MURAL RESEARCH
Search for Potential Anticancer Agents: Evaluation of Anticancer Activity of Carcinosin, Apis and Thuja
Soma Samanta, AU De, PK Tarafder, Tarun Jha
January-March 2008, 2(1):38-41
As a part of our composite programme of rational drug discovery, homeopathic medicines Carcinosin, Apis and Thuja with different strengths were taken into consideration for anticancer activity to find out the effectiveness of these drugs in animal models. Here, we have reported the anticancer activity of Carcinosin of some strengths from a manufacturer where tumor cell count as well as tumor weight inhibition were considered as the biological activity parameters. Anticancer activity of all collected medicines of Carcinosin, Apis and Thuja were evaluated against another animal model considering the survival time as the biological activity parameter. Result showed that the survival time of Carcinosin is proportionally increased with potency and the observed result also satisfies the validity of the animal model for anticancer evaluation as well as supports our earlier observations. Apies and Thuja did not show promising result to increase the survival time.
  1,086 273 -
FUNDAMENTAL RESEARCH
Application of HPTLC in the Standardization of a Homoeopathic Mother Tincture of Nux Vomica
DA Shanbhag, Sunita Jayaraman
January-March 2008, 2(1):1-7
In this study,we have chosen HPTLC (High Performance Thin Layer Chromatography) as a method of analysis to develop a standard procedure based on fingerprinting characteristics for the evaluation of homreopathic formulations. A simple and accurate HPTLC method has been developed for the quantification of brucine,one of the chief active chemical components of Nux vomica (along with strychnine),and the fingerprinting of the in-house mother tincture of Nux vomica, considered here to be a standard, with that of different marketed samples available from manufacturers of homreopathic medicines in India. This HPTLC method was quantitatively evaluated in terms of stability, repeatability, and accuracy.
  987 214 -
DRUG STANDARDISATION
Standardisation of Homoeopathic Drugs – Castanea Sativa Mill.
PP Rao, P Subramanian, PR Reddy, KJ Reddy
January-March 2008, 2(1):8-12
Castanea sativa Mill. A tree belonging to the family Fagaceae is a potential drug in Homoeopathy. The leaves are used as tonic, astringent, In paroxysmal coughs and diarrhoea. The leaves are large, lanceotate with deep serrate margins and covered by indumentum on the lower side. The epidermis has cells with thick straight to curved or wavy sides. Stomata are actinocytic or anomocytic. The abaxial side has dense hairy cover consisting of 2-6 armed and stellate hair. In T.S. the ratio of midvein to lamina is 6:1. Sphaeraphidal idioblasts are present in the cortical perenchyma and pith of midvein and petiole. The vascular tissue appears in the form of a plectostele in the midvein end petiole. Besides, powder microscopical and organoleptic characters are presented. Physico-chemical parameters of raw drug viz., extractive values, ash values, formulation, besides. Wt. per ml, total solids, alcohol content and T.L.C. and U.V. studies are given for mother tincture.
  976 184 -
EDITORIAL
Editorial
C Nayak
January-March 2008, 2(1):0-0
  781 146 -
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