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  Most popular articles (Since June 29, 2013)

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To evaluate the role of homoeopathic medicines as add-on therapy in patients with rheumatoid arthritis on NSAIDs: A retrospective study
Tapas K Kundu, Afroz F Shaikh, Sindhu M Jacob
January-March 2014, 8(1):24-30
Background: Conventional management of Rhematiod Arthritis (RA) includes administration of Non- Steroidal Anti- Inflammatory Drugs (NSAIDs), disease modifying anti-rheumatic drugs (DMARDs) like Methotrixate and anti-tumor necrosis factor α monoclonal antibody (anti-TNFά). Gastric ulcers, bleeding and perforation are the most common known adverse reactions found associated with excessive consumption of NSAIDs. The homoeopathic system of medicine improves the general well being, that is, Quality of Life (QoL) in addition to reducing the pain and disability. Objective: To evaluate the patients with RA receiving homoeopathic medicines with respect to QoL, Disease Activity Score (DAS), Erythrocyte Sedimentation Rate (ESR), morning stiffness/pain and frequency of analgesics after homoeopathic intervention. Design: This is a retrospective analysis of the role of homoeopathic medicines in RA. Patients diagnosed as sero-positive for RA antigen receiving homeopathic medicines were analysed for DAS, QoL, frequency of analgesics, ESR and pain/morning stiffness. Materials and Methods: Ten cases testing sero-positive for RA with at least four clinical signs were evaluated from single homoeopathic Out-Patient Department (OPD) from February 2009 and February 2011. Cases were analysed to find out the role of homoeopathic constitutional similimum in people with RA. Changes in DAS, ESR, pain/morning stiffness and QoL were considered as outcome measure. Results: Homoeopathic constitutional medicines were found to reduce the intensity of pain in patients with RA (t = 4.3733, P < 0.01) along with reduction in consumption of NSAIDs (t = 2.4, P < 0.05). The DAS reduced in all 10 patients (t = 2.67, P < 0.01). The QoL was also found to improve under homoeopathic medication (t = 4.044, P < 0.01) and no further deterioration joint/disability was observed in any of the 10 patients. Mean ESR improved to 19.5 from 38.1 (t = 2.235, P < 0.05). Out of 10, 3 (30%) patients were found to be sero-negative after homoeopathic constitutional similimum. Conclusion: Homoeopathic constitutional similimum improves the QoL of patients with RA by reducing intensity of pain, limiting disability and reducing disease activity, thus causing improvement in general and disease condition in particular. It also limits the need of analgesics and DMARDs in RA.
  84,611 10,449 2
Evidence-based homoeopathy: A case of acute paraphimosis with balanitis
Chinta Raveendar, Kishan Banoth
July-September 2013, 7(3):133-136
Paraphimosis occurs when the foreskin of the uncircumcised or partially circumcised male is retracted behind the glans penis, develops venous and lymphatic congestion and cannot be returned to its normal position. This urological emergency impedes blood flow to the glans penis with potential for permanent damage and gangrene. In infants and young children, paraphimosis usually results from self-manipulation by the child or inappropriate retraction of the foreskin by the caretaker in misguided attempts at cleaning. In the sexually active adolescent or adult male, intercourse is a potential precipitant. Iatrogenic paraphimosis follows cystoscopy or bladder catheterisation if the foreskin is not pulled back over the glans penis by the medical provider. This surgical intervention can be avoided through homoeopathic treatment. A case of paraphimosis with balanitis of an adolescent treated with homoeopathy is reported here. This case shows the usefulness of homoeopathic medicines, Apis mellifica, Rhus toxicodendron, Cinnabaris and Mercurius solubilis, in not only giving symptomatic relief to the patient but also restoring the foreskin completely to its normal position.
  91,632 1,449 1
A study of the effect of mother tincture of Syzygium jambolanum on metabolic disorders of Streptozotocin induced diabetic male albino rat
Soumyajit Maiti, Tushar Kanti Bera, Kausik Chatterjee, Debidas Ghosh
July-September 2014, 8(3):129-135
Background: Syzygium jambolanum is widely used in Homoeopathy for treating Diabetes mellitus and its complications. Objective: To explore the remedial effects of homoeopathic mother tincture Syzygium jambolanum on metabolic disorders of Streptozotocin induced diabetic male albino rat. Materials and Methods: Serum levels of insulin, urea, uric acid, creatinine, albumin and total protein were measured as per the standard methods using specific kits. Amount of glycogen in liver and skeletal muscles, activities of antioxidant enzymes as well as content of free radical bye products in liver and kidney tissues were assessed biochemically following the standard protocol. Results: The study indicated that the treatment of mother tincture of Syzygium jambolanum in diabetic albino rats restored the body weight and significantly controlled the elevated blood glucose level as compared with the untreated group. Levels of glycogen in liver and skeletal muscle tissues were recovered by treatment with Syzygium jambolanum in diabetic rats as compared with the untreated diabetic rats. Levels of serum urea, uric acid and creatinine were increased in diabetic rats significantly as compared with the control group, which were resettled in the control group after treatment with mother tincture of Syzygium jambolanum in diabetic animals. Alongside, significant recovery in the activities of antioxidant enzymes like catalyse, peroxidase and super oxide dismutase, the levels of free radicals generated as bye products in hepatic and renal tissues were also observed in the treatment with mother tincture of Syzygium jambolanum treated diabetic animals with respect to the untreated in diabetic animals. Conclusion: The homoeopathic mother tincture of Syzygium jambolanum has therapeutic effect on metabolic disorders and oxidative injuries in Streptozotocin induced diabetic male albino rats.
  90,055 1,746 -
Homoeopathic medicine Mercurius solubilis treatment improves cerebral blood flow and memory in experimentally induced Dementia in rats
Kashif Hanif, Manoj Kumar, Neetu Singh, Rakesh Shukla
January-March 2017, 11(1):58-63
Background: Mercurius solubilis (Merc. sol) is a known, accepted homoeopathic medicine for the treatment of various mouth, throat, eye, and ear infections. Previous studies suggested that Merc. sol has anti-inflammatory properties which could be beneficial in memory impairment. Objective: The present study was designed to investigate the effect of Merc. sol on learning and memory and cerebral blood flow (CBF) in the rat model of impaired learning and memory function induced by intracerebroventricularly (ICV) administered streptozotocin (STZ). Materials and Methods: The different potencies of Merc. sol (6, 30, 200, and 1M) were given for 17 days in memory-impaired rats, induced by ICV administration of STZ (3 mg/kg). The Morris water maze test was used to evaluate the learning and memory function on the 14th, 15th, and 16th day. The laser doppler flow meter was used to measure CBF on the 17th day. Results: There was a significant reduction in CBF along with learning and memory functions in STZ (ICV)-treated rats, which were significantly attenuated by the treatment of Merc. sol at all potencies (6, 30, 200, and 1M). Conclusion: Our results demonstrated the effectiveness of Merc. sol in improving memory function and CBF. Thus, it could be used as a therapeutic agent in dementia.
  89,819 829 -
Homoeopathic approach for the treatment of cancer
Saeed Ahmad, Tayyeba Rehman, Waheed Mumtaz Abbasi
July-September 2018, 12(3):157-163
Homoeopathy is among the commonly used alternative approaches in Cancer. It is being widely used as palliative and curative in patients suffering from cancer. Though studies on the use of Homoeopathy in cancer after surgery, radio therapy and chemotherapy have been reported, clinical trials on effects of Homoeopathy in cancer are rare. Some studies on the effect of dosage of Homoeopathic medicines and their mechanism of action in cancer have also been published. A few case reports published here and there also find a mention in different databases. This review aims to describe literature available on the approach of Homoeopathy in Cancer by searching various databases like Elsevier, Google Scholar, Pub Med, Scopus, Springer and Wiley online library, electronically. It was found that beneficial effect of Homoeopathic medicines are reported on some cancer cell lines via apoptosis and immune modulation. Homoeopathic treatment given as add on also improves the quality of life, survival time and presenting complaints. However, more evidence needs to be generated to demonstrate anti tumor or antimetastatic potential in controlled clinical trials.
  71,803 1,718 -
Gangrene: Five case studies of gangrene, preventing amputation through Homoeopathic therapy
Seema Mahesh, Mahesh Mallappa, George Vithoulkas
April-June 2015, 9(2):114-122
Gangrene and its associated amputations are clinically challenging, but Homoeopathy offers therapy options. In this case series, 5 cases are presented, in which the homoeopathic treatment prevented amputation of a body part. Homoeopathy stimulates the body's ability to heal through its immune mechanisms; consequently, it achieves wound healing and establishes circulation to the gangrenous part. Instead of focusing on the local phenomena of gangrene pathology, treatment focuses on the general indications of the immune system, stressing the important role of the immune system as a whole. The aim was to show, through case reports, that homoeopathic therapy can treat gangrene without amputing the gangrenous part, and hence has a strong substitution for consideration in treating gangrene.
  57,909 2,587 3
Effectiveness of homoeopathic therapeutics in the management of childhood autism disorder
Praful M Barvalia, Piyush M Oza, Amit H Daftary, Vijaya S Patil, Vinita S Agarwal, Ashish R Mehta
July-September 2014, 8(3):147-159
Background and Objectives: Childhood autism is severe and a serious disorder. A study was conducted by Spandan holistic institute of applied Homoeopathy, Mumbai, with the objective of demonstrating the usefulness of homeopathic management in autism. Materials and Methods: Sixty autistic children of both sexes, ≤12 years were selected for this study. It was nonrandomized, self-controlled, pre and post-intervention study, wherein the initial 6 months of observation period was used as the control period and the same patients were thereafter treated for 1 year and compared with post-intervention findings. Results: The study demonstrated significant improvement of autistic features with mean change in ATEC score (ATEC 1 -pre-treatment with ATEC 5 -post-treatment) was 15.12 and ATEC mean percent change was 19.03. Statistically significant changes in ATEC scores were observed in all the quarters analyzed through repeated measures ANOVA, with F-value 135.952, P = 0.0001. An impact was observed on all core autistic features, which included communication, 12.61%, socialization, 17%, sensory awareness, 18.82%, and health and behavior, 29% (P = 0.0001). Significant improvement was observed in behavior by Autistic Hyperactivity Scale, AHS 1 36 to AHS 5 14.30 with F-value 210.599 (P = 0.0001). Outcome assessment was carried out using MANOVA, which showed statistically significant changes in post-treatment scores, P < 0.005. Total 88.34% cases showed improvement, 8.33% showed status quo, and 3.33% cases worsened. Nine out of 60 cases showed a reversal of CARS putting them into non-autistic zone, P = 0.0001. A sharp decrease (34%) in ATEC scores, in the first quarter implied positive effect of homoeopathic medicines, prescribed, as per the homoeopathic principles. Conclusion: The study has demonstrated usefulness of homoeopathic treatment in management of neuropsychological dysfunction in childhood autism disorder, which is reflected in significant reduction of hyperactivity, behavioral dysfunction, sensory impairment as well as communication difficulty. This was demonstrated well in psychosocial adaptation of autistic children.
  49,879 7,994 4
Management of PCOS through Homoeopathy-A case report
Padmalaya Rath
April-June 2018, 12(2):95-100
Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects approximately 5% of all women which are very commonly found in day-to-day (routine) practice. However, these cases present with many complications and it is difficult to cure in contemporary system and treatment is also very costly. A case of 22 years female suffering from PCOS reported here was treated successfully within 1.5 years by a single individualised homoeopathic medicine Calcarea cabonicum 30-1M with repetition as per requirement, The improvement is evident from regularity of menstrual cycle and also from the ultrasonography (USG) reports. The case was observed for further 3 years without recurrence which suggests that permanent cure is achievable through individualised homoeopathic treatment.
  48,525 1,389 -
Dengue epidemic: What can we offer?
Raj K Manchanda
July-September 2015, 9(3):137-140
  42,586 1,548 2
Role of homoeopathic mother tinctures in rheumatoid arthritis: An experimental study
Surender Singh, Ritu Karwasra, Prerna Kalra, Rohit Kumar, Shalu Rani, Debadatta Nayak, YK Gupta
January-March 2015, 9(1):42-48
Objectives: The objective of present preliminary study was to assess the anti-inflammatory, analgesic and anti-arthritic effect of some homoeopathic mother tinctures viz. Ricinus communis (RCMT), Rauwolfia serpentina (RSMT), Bellis perennis (BPMT), Curcuma longa (CLMT), Terminalia arjuna (TAMT) and Tribulus terresteris (TTMT). Materials and Methods: Paw oedema was induced by administration of 0.1ml 1% carrageenan in normal saline into right hind paw. Degree of inflammation was evaluated according to paw swelling. Arthritis was induced by Complete Freund's Adjuvant (CFA) injection in metatarsal footpad of Wistar albino rats. Result: Curcuma longa and Tribulus terresteris mother tinctures reduced hind paw swelling decreased the paw volume in Carrageenan treated rats. Thus, revealed potent activity against inflammation. All homoeopathic mother tinctures showed peripheral analgesic activities in hot plate induced thermal algesia in mice.
  37,480 1,786 2
Case studies for treatment of warts with Homoeopathy
Md Ismail Shaikh
October-December 2016, 10(4):272-278
Warts are the growth of skin resulting from human papillomavirus infection. These may be single, multiple, smooth, or cauliflower-like and are generally treated by applying medicine externally or surgical excision procedure. Homoeopathy has a major role in the treatment of warts and most of the homoeopathic doctors use medicine in centesimal potencies. Five cases of warts were treated, two cases with centesimal potencies, and three cases treated with fifty millesimal potencies. Cases treated with fifty millesimal potencies responded more quickly than centesimal potencies without aggravating the complaints and without applying any external medicines. There is a possibility that fifty millesimal potencies have higher beneficial effects, in the treatment of warts, which can be explored further.
  35,653 2,132 -
Homoeopathic preparation of Berberis vulgaris as an inhibitor of Calcium oxalate crystallization: An in vitro evidence
Thellamudhu Ganesan, Divya Bhavani Ravi, Jyothilakshmi Vasavan, Anil Khurana, Debadatta Nayak, Kalaiselvi Periandavan
July-September 2015, 9(3):152-157
Background: Berberis vulgaris is the most widely used drug in Homoeopathy for treating urolithiasis. However, its mechanism of action in alleviating its consequences remains uncertain. Objective: To explicate the potential role of Homoeopathic preparation of B. vulgaris on in vitro Calcium oxalate (CaOx) crystallization. Materials and Methods: Spectrophotometric crystallization assay was carried out, and the slopes of the nucleation (till the maximum) and aggregation (after the peak) phases were calculated using linear regression analysis, and the percentage inhibition exerted by the modifiers was calculated. Light microscopic observation of CaOx crystals formed in the presence or absence of modifiers was carried out to support the outcome with spectrophotometric crystallization assays and to ascertain the potential role of B. vulgaris in CaOx crystallization. Results: The crystallization studies performed so far signifies B. vulgaris to be a potent drug against CaOx crystallization both at the level of nucleation and aggregation. Conclusion: Our present findings add up to the experimental evidence to support the efficacy of the homeopathic preparation of the B. vulgaris in modulating the primary events of stone formation.
  36,204 935 -
Homoeopathic management of Schizophrenia: A prospective, non-comparative, open-label observational study
Praveen Oberai, S Gopinadhan, Anita Sharma, Chaturbhuja Nayak, Kalpana Gautam
April-June 2016, 10(2):108-118
Objectives: To evaluate the usefulness of homoeopathic intervention in Schizophrenia, in untreated cases and antipsychotic treatment resistant cases, to verify indications of medicines, and to assess relapse, if any. Materials and Methods: A prospective, non-comparative, open-label observational study was carried out from October 2005-September 2010 by CCRH at Central Research Institute (H), Kottayam, Kerala, India. Patients between 20 and 60 years of age, presenting with symptoms of Schizophrenia were screened for inclusion and exclusion criteria. The patients who were on antipsychotic drugs were allowed to continue the same along with homoeopathic medicine, the dose of antipsychotics was monitored by the Psychiatrist. The symptoms of each patient were repertorized, and medicine was initially prescribed in 30C potency after consulting Materia Medica. Patients were followed up for 12 months. Outcome of treatment was assessed with Brief Psychiatric Rating Scales (BPRS). Analysis was done using Statistical Package for the Social Sciences  SPSS Version 20.0. Results: Out of 188 enrolled patients, 17 cases did not complete the baseline information. Total 171 patients were analysed as per modified Intention to Treat Principle. Significant difference (P = 0.0001, P < 0.05) in the mean scores of BPRS, using paired t test was observed at end of the study. Sulphur, Lycopodium, Natrum muriaticum, Pulsatilla and Phosphorus were found to be the most useful medicines in treating schizophrenic patients. Conclusion: The study reflects the positive role of homoeopathic medicines in the management of patients suffering from schizophrenia as measured by BPRS.
  35,423 1,287 2
Antidiabetic effect of Cephalandra indica Q in diabetic rats
Arindam Pal, Biswapriya B Misra, Shibendu S Das, Samiran S Gauri, Moumita Patra, Satyahari Dey
April-June 2013, 7(2):81-90
Background: Diabetes mellitus is an emerging global epidemic, taking its toll in developing countries as India. Presently, the treatment for diabetes using allopathic drugs gives only a temporary relief. A combination of right medicine and potency, on other hand has given Homoeopathy a high success rate in the treatment of this disease. Objective: The aim of this study was to investigate the effects of Cephalandra indica mother tincture and potencies on blood glucose level, cholesterol level, body weight, and beta-cells of pancreatic islets of Langerhans, in streptozotocin (STZ)-induced diabetic Wistar rats. Material and Methods: Glucose uptake was monitored in mother tincture-treated mouse fibroblast cell line. Diabetes mellitus was induced by intraperitoneal injection of STZ (55 mg/kg body weight) in adult male rats. After three days of injection, diabetic rats received mother tincture orally (750 μL/kg body weight) daily for three weeks. Results: There was a significant reduction of blood glucose level, regain of body weight, and regeneration of beta-cells in the pancreas of the mother tincture-treated rats. Mother tincture-treated 3T3 cells also showed reduced uptake of glucose in comparison to normal cells. Conclusion: The present study clearly indicates a significant antidiabetic effect of Cephalandra indica and lends support for its usage as a homoeopathic medicine.
  34,851 1,412 1
Homoeopathic treatment of ulcerative Colitis: A case report
Partha Pratim Pal, Madhu Sudhan Ghosh, Abhijit Chakma
January-March 2017, 11(1):74-78
Ulcerative colitis (UC) is one of the most common inflammatory bowel diseases. As in most of the cases, the exact cause is unknown Homoeopathy, however, provides a better response in such conditions, one such case report is presented below. Patient attended out patient department (OPD) chiefly for complaints of frequent passage of bloody stool and abdominal pain. He was suffering from idiopathic UC for the past 10 years. After unsatisfactory outcome with modern medicine, patient turned to homoeopathic treatment. After detailed case-taking and repertorization, Hydrastis was given in low potency, and gradually, the potency was raised as per the response of the medicine upon patient. Within 3–4 months of homoeopathic treatment, the patient started improving and continues to be free from his complains at the time of last follow-up visit in OPD.
  34,725 1,164 -
A retrospective study of homoeopathic treatment in patients with heel pain with or without Calcaneal Spur
Suraia Parveen
January-March 2017, 11(1):64-73
Background: Heel pain is a common clinical condition which significantly affects the quality of life. It is frequently associated with calcaneal spur (CS). Despite its high prevalence, the optimal treatment remains unclear. The aim and objective of this study is to evaluate the extent of CS in heel pain; correlation of CS with some sociodemographic and health-related factors; and outcome of homoeopathic treatment over a period of 6 months. Methodology: It was a retrospective study done at Dr. Anjali Chatterjee Regional Research Institute for Homoeopathy, Kolkata. Samples were selected from the patients referred for ankle X-ray from August 2014 to July 2015 for nontraumatic heel pain. Their files were traced from outpatient department, and treatment records were reviewed over the next 6 months. Results: Totally 92 patients, 70 women and 22 men, had undergone lateral X-ray of ankle for nontraumatic heel pain, of which 76 (82.6%) patients had CS. Extent of CS was found to be higher in case of females, older age, overweight, and profession of housemaid or manual labor. Homoeopathic treatment showed positive response in nearly 75% of the CS patients. The most useful medicines were Calcarea flouricum, Rhus toxicodendron, Ledum palustre, and Aranea diadema. Conclusion: CS was found in nearly 80% of patients presenting with heel pain, which showed association with female sex, overweight, increasing age, and profession requiring heel stress. Homoeopathic treatment was effective in 3/4th of CS patients, and Rhus toxicodendron and Calcarea flouricum are the two most commonly used medicines.
  30,089 1,152 -
Individualized homoeopathic treatment of breast fibroadenoma: A case report
Suraia Parveen
January-March 2018, 12(1):46-52
Fibroadenoma is the commonest benign breast tumor in adolescent and young women. Conservative management with regular observation is the rule for newly diagnosed patients. For progressive growth in young patients or failure of regression in patients above 35 years surgical intervention is contemplated. But there may be recurrence after surgery and patients are often apprehensive of surgery. Here, a 18-year-old girl presented with a palpable, non-tender, movable lump in the left breast at upper outer quadrant progressively increasing in size over last 2 years and was advised for surgery. Sonomammography and FNAC confirmed it as simple fibroadenoma (3.48 × 2.38 centimeter). She was successfully treated by individualized homoeopathic treatment with single medicine Pulsatilla nigricans over 15 months. Serial Sonomammography reports revealed progressive regression of Fibroadenoma to non palpable state. Possible causal attribution of changes was explicitly depicted by Naranjo Criteria. It shows positive role of Homoeopathic treatment in regression of fibroadenoma in a young woman.
  29,689 895 1
A case report of fibroadenosis alleviated with Homoeopathy
Bharti Wadhwa
July-September 2017, 11(3):196-202
Fibroadenosis also known as fibrocystic breast disease constitutes the most frequent benign disorder of the breast causing constant breast pain. The only known treatment in conventional medicine is anti-inflammatory medicines which give temporary relief or surgical excision which results in scarring of breast tissue. The homoeopathic literature shows that cases related to breast lump, mastitis, etc. have been treated successfully; however, no case study/research trial has been documented till date in any peer-reviewed journal. The case reported here is of fibroadenosis in 31-year-old female who was treated successfully with individualised homoeopathic medicine within 6 months with no recurrence. Phytolacca was prescribed as a constitutional remedy on the basis of totality of symptoms and after repertorisation. Investigatory procedures such as mammography and ultrasonography were done before and after to record resolution of cysts. The patient has been observed for more than 1 year without recurrence which can be considered as near permanent cure through individualised homoeopathic treatment. Resolution of cysts in this case of fibroadenosis with Homoeopathy can be considered a lead to explore the utility of alternative modes of treatment such as Homoeopathy to give a better therapeutic option for such surgical conditions.
  24,106 700 -
Scientific method of preparing homoeopathic nosodes
Rajesh Shah
July-September 2014, 8(3):166-174
Introduction: Nosodes are homoeopathic preparations sourced from biological materials such as diseased tissues, organisms, cultures (bacteria, fungi, and viruses), or parasites, or from decomposed products from humans or animals. More than forty-five major nosodes have been in use since 1830 but no clear guidelines regarding their preparation are available. Objective : To standardize the method of preparation of nosodes using modern technology and lay down clear guidelines for the same. Materials and Methods : Biological material identification such as culture of organism, separation of required pure fraction, quantification, standardization, dilutions, potentisation method, and safe use of nosodes were documented in a systematic way . Result: HIV, HCV and Mycobacterium tuberculosis nosodes were prepared using the modified method described in this article. Conclusion: The improved method of nosode preparation can pave way for laying clear guidelines for preparation of nosodes in homoeopathic pharmacopeias.
  20,812 1,493 8
Anti-candidal activity of homoeopathic drugs: An in-vitro evaluation
Girish Gupta, AK Srivastava, Naveen Gupta, Gaurang Gupta, Sunil Mishra
April-June 2015, 9(2):79-85
Background: Candida albicans is an opportunistic pathogenic fungus accounting for up to 75% of all candidal infections in human beings. Generally Candida grow and survive as commensals but slight modification of the host defense system can transform Candida albicans into a pathogen. Materials and Methods: Samples collected from the oral cavity and tongue of the patients suspected of suffering from oral candidiasis were incubated for growth of Candida. Fermentation and assimilation test confirmed the species as Candida albicans. Disc method was used to assess the in-vitro anti-candidal effect of few homoeopathic drugs in 30 and 200 potencies against human pathogenic Candida albicans under in-vitro conditions and compared with standard antifungal drug ketoconazole (control), rectified spirit (control/vehicle) and distilled water (vehicle) by "inhibition zone technique". Results: Homeopathic drugs namely Acid benzoicum, Apis mellifica, Kali iodatum, Mezereum, Petroleum, Sulphur, Tellurium, Sulphur iodatum, Graphites, Sepia, Silicea and Thuja occidentalis in 30 and 200 potencies were tested against Candida albicans. Mezereum in 200 and 30 potency showed maximum inhibition of growth of Candida albicans followed by Kali iodatum 200 while Kali iodatum 30 and Petroleum 30 had minimum inhibition. Conclusion: The results of these experiments support the concept of "evidence based medicine" depicting that homoeopathic medicines not only work in in-vivo but are equally effective in in-vitro conditions having definite inhibitory activity against Candida albicans.
  19,165 1,049 1
Homoeopathic treatment in a case of co-morbid atopic dermatitis and depressive disorder
Suraia Parveen
January-March 2016, 10(1):75-82
Atopic dermatitis (AD) is a skin disease characterized by itching, typical morphology, and distribution of rash, chronic relapsing course, and personal or family history of “atopic diathesis.” Stress is an important precipitating factor of AD. Stress has also some causal link with depression. Rationale of this case report is to demonstrate the co-occurrence of AD and depression in a patient, and better improvement of AD occurs when homoeopathic treatment focuses on psychological symptoms. Here, a 38-year-old male presented with a 6-month history of eczematous skin lesions with associated symptoms of depression in the background of chronic ongoing stress. A diagnosis of AD with comorbid depression was made. He initially did not show stable improvement on homoeopathic medicine selected on the basis of totality of symptoms and miasmatic background. On changing the medicine giving more priority to psychological symptoms, he gradually showed stable improvement on both the domain of symptoms and reached remission by 3 months. Remission maintained without any recurrence over the next 3½ years. Hence, the main lesson from this case is the demonstration of importance of mental symptoms over other physical symptoms in homoeopathic treatment.
  17,750 769 -
A comparative study of homoeopathic medicine - Sulphur with the Multidrug therapy in the treatment of paucibacillary leprosy
D Chakraborty, P Das, AK Dinda, U Sengupta, T Chakraborty, J Sengupta
July-September 2015, 9(3):158-166
Background: Substantial number of patients with paucibacillary leprosy may still have active skin lesions at the end of MD treatment because of the continuing immune responses, though this does not denote failure of treatment. A clinical trial was conducted to compare efficacy of a homoeopathic medicine with MDT for the cure of leprosy. Aim: To compare the effect of a homoeopathic medicine - Sulphur with the Multi drug in the treatment of Paucibacillary leprosy according to WHO guidelines. Materials and Methods: Out of total 90 patients enlisted, 60 confirmed Borderline Tuberculoid (BT) leprosy patients of the age 14 years to less than 60 years were registered under this trial. All the patients were allotted a precoded number, randomly and equally divided in two groups. One group was treated with Sulphur in 200 potency in liquid orally once in week for two years and the other group received Paucibacillary (PB) regimen as recommended by WHO. At the end of two years findings were corroborated. Results: The study showed that MDT therapy (PB regimen) and homoeopathic medicine were found equally effective as histopathology of skin showed no granulomatous lesion. The most significant clinical sign observed in all cases treated with Sulphur was reappearance of normal skin colour and regain of loss of sensation of the skin lesion. Conclusions: MD therapy (PB regimen) and homoeopathic medicine were found equally effective. The patients of paucibacillary leprosy could get rid of the skin symptoms if treatment with Sulphur (is also given with MDT).
  16,958 870 1
Evaluating the usefulness of 50 millesimal potencies in the treatment of chronic diseases - A retrospective study
S Abarna, Jayakrishnan Venugopal, T Sivaranjani, Kurian J Poruthukaren, Praveen Raj, Sucharitha Suresh
April-June 2015, 9(2):96-101
Introduction: The 50 millesimal potency, is not fully utilized in our day to day practice. This retrospective study was done to reveal a new horizon for the physicians who use it occasionally and an eye opener for those who have never tried it. Aim: The aim was to evaluate the usefulness of 50 Millesimal potency of indicated medicine in the treatment of chronic diseases from a retrospective study. Materials and Methods: Cases treated with 50 Millesimal potency (LM) during January-May 2014, were screened and based on eligibility criteria, 50 cases were selected to study retrospectively. Treatment outcome was analyzed based on follow-up criteria. Data were statistically analyzed with Chi-square test in GNU PSPP Software. Results: 50 Millesimal potencies have the potential to give significant improvement (P = 0.01) in the treatment of chronic diseases. There were no cases reported with aggravation. The action of LM potency is not influenced (P = 0.97) by previously used Centesimal potency. Constitutional prescription has proved to have significant (P = 0.01) association with treatment outcome with LM potency, whereas Sector prescription (P = 0.12) does not. Irrespective of age, gender, and duration of illness, 50 Millesimal potencies act advantageously. Conclusion: The data suggest that 50 Millesimal potencies have significant beneficial effects in the treatment of chronic diseases.
  16,268 1,363 -
Role of homoeopathic medicines in prostate enlargement: A retrospective observational study
Girish Gupta, Santosh Singh
October-December 2016, 10(4):266-271
Background: Prostatic enlargement (prostatomegaly) is a common condition in aging men which can be progressive and lead to acute urinary retention and ultimately need for surgery. Although clinical evidence of disease occurs less commonly, symptoms of prostatic obstruction are also age related and if untreated affect quality of life. Patients with huge prostatic enlargement mostly undergo surgical intervention. Objective: To assess the usefulness of homoeopathic medicines in patients with huge prostatomegaly, a clinical study was conducted at Gaurang Clinic and Centre for Homoeopathic Research, Lucknow, India. Materials and Methods: A total of 116 patients have been shortlisted with prostate weight above 50 g, out of which 61 were found fit for the study. The medicines have been selected on the basis of principles of Homoeopathy. Prostate weight and postvoid residual urine (PVRU) on ultrasonography were assessed before and after treatment. Results: After comparing pre- and post-treatment results, the difference in mean values of prostate weight and PVRU were 67.47 ± 2.78-60.15 ± 3.62 (P < 0.001) and 91.61 ± 11.91-65.94 ± 9.01 (P = 0.009), respectively, which were found statistically significant. Lycopodium (n = 21), Pulsatilla (n = 7), and Nux vomica (n = 3) were found to be most useful medicines. Conclusion: Results obtained from the study are encouraging with findings that almost 64% of patients reduced their prostatic weight significantly. However, such study with inclusion of more parameters is needed for further validation of the role of homoeopathic medicines.
  16,802 801 1
Evaluation of antiobesity activity of Fucus vesiculosus
Vishnu Priya Korukanti, Himabindu Ponnam, Butchi Raju Akondi
July-September 2013, 7(3):126-132
Background and Aim: The drug Fucus vesiculosus is used in alternative system of medicine and homoeopathy, for the treatment of obesity. But in homoeopathic literature survey, we found no substantial pharmacological evidence to prove its safety and efficacy. So, the study was taken up on this drug and evaluated it on different animal models (diet-induced and chemical-induced models) of obesity. Material and Methods: Obesity was induced in adult female Wistar albino rats (100-120 g) by feeding the rats with cafeteria diet for 42 days in diet-induced model and by administration of single intraperitoneal injection of Triton X-100 in chemical-induced model. In the diet-induced model, weight of the animals was measured every week and parameters like total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and high density lipoprotein (HDL) were measured on 0, 21 and 43 days. Further, locomotor activity was assessed for all the animals on 43 rd day. On the same day, the rats were sacrificed by cervical dislocation and their organ and fat pad weights were recorded. In the chemical-induced model, the above parameters were assessed on day 0 and day 8. Results: Feeding cafeteria diet for 42 days resulted in significant increases in the body weight, TC, TG, LDL and VLDL levels and a reduction in the HDL level. Further, the locomotor activity was found to be reduced significantly. Treatment with Fucus vesiculosus significantly protected the cafeteria diet fed animals from all these changes and helped to maintain normal locomotor activity. Similar results were observed in chemical-induced obesity model also. Conclusion: Fucus vesiculosus treatment prevented the rats from becoming obese and the biochemical and physical parameters were maintained to normal levels. So, the drug Fucus vesiculosus can be taken up for further research on human subjects.
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