• Users Online:1049
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2012  |  Volume : 6  |  Issue : 2  |  Page : 1-7

Indigofera tinctoria: Preliminary experimental study evaluating its analgesic and behavioural activities in animals

1 Central Research Institute (H), Noida, India
2 Drug Standardisation Unit (H), Hyderabad, India
3 Departments of Zoology, Osmania University, Hyderabad, India
4 Central Research Institute (H), Kottayam, India
5 Central Council for Research in Homoeopathy, New Delhi, India

Correspondence Address:
E N Sundaram
Central Research Institute (H), A-1/1, Sector - 24, Noida - 201301. Uttar Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Indigofera tinctoria Linn. (Family: Fabaceae) is traditionally used for the treatment of various ailments including nervous disorders. In homoeopathy too, I. tinctoria is used in the treatment of epilepsy and other nervous disorders, but no data has been scientifically documented to establish its central nervous system activities. In the present preliminary study, the different potencies (3x, 6x, 12x and 30c) of I. tinctoria administered at a dose of 0.5 ml/rat/day were evaluated for their analgesic (hot plate, ice plate and Randall -Selitto tests) and behavioural (rota rod and open field tests) activities. The results revealed that all the four potencies of I. tinctoria had increased the latency time required to raise and to lick the fore or hind paw for thermal sensation on hot plate test and for cold sensation on ice plate test. They had also increased the quantum of threshold pressure to mechanical induced pain on Randall -Selitto test but depressed the motor coordination and locomotor activities. The observed activities suggest that the homoeopathic formulations of I. tinctoria possess CNS depressant property. However, further studies are required for a definitive conclusion.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded232    
    Comments [Add]    

Recommend this journal