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 Table of Contents  
FUNDAMENTAL RESEARCH
Year : 2009  |  Volume : 3  |  Issue : 1  |  Page : 1-5

Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study


1 Federal University of Rio de Janeiro, Brazil
2 University of Rio de Janeiro, RJ, Brazil

Date of Web Publication2-Apr-2014

Correspondence Address:
(DSc) Carla Holandino
Federal University of Rio de Janeiro
Brazil
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Source of Support: None, Conflict of Interest: None


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  Abstract 

The latex extracted from Euphorbia tirucalli, a plant popularly known as Aveloz, is used in complementary medicine to induce tumor regression. However, as this latex has toxic effects when administered orally in ponderal doses, the present study was designed to assess the effects of high dilutions in healthy mice over a period of 18 weeks. The Aveloz latex-high diluted solutions (latex-HD) were obtained through the interaction of two processes: 1:100 dilution in mass and succussion, using ethanol 70% as a solvent, in the homeopathic dilutions of 5, 15 and 30cH, following Farmacopéia Homeopática Brasileira. Control solutions without latex were compounded (ethanolic-HD) in the same dilutions and were administered simultaneously. The animals which received latex-HD 30cH showed a significant increase in food consumption (p < 0.05) without significant difference in weight gain. In regards to water consumption, no statistical difference was shown when different Aveloz latex-HD groups were compared, apart from the group that received 1 drop of pure latex in water, which presented a significant increase (p < 0.05) in this parameter.

Keywords: Euphorbia tirucalli; Aveloz; Toxicology; High Dilutions; Mice


How to cite this article:
Varricchio MC, Pereira C, Sales F, Gomes T, Daudt E, Aquino CL, Barbosa GM, Gomes N, dos Santos Pyrrho A, Hobaica PE, Branco MC, Kuster R, Holandino C. Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study . Indian J Res Homoeopathy 2009;3:1-5

How to cite this URL:
Varricchio MC, Pereira C, Sales F, Gomes T, Daudt E, Aquino CL, Barbosa GM, Gomes N, dos Santos Pyrrho A, Hobaica PE, Branco MC, Kuster R, Holandino C. Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study . Indian J Res Homoeopathy [serial online] 2009 [cited 2019 Sep 15];3:1-5. Available from: http://www.ijrh.org/text.asp?2009/3/1/1/130027

∗This article was originally published in the journal 'International Journal of High Dilution Research', 2008; 7(25): 174-178: Reprinted with the consent of the author and the publisher.


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